Published July 1, 2008.
287 Pages - $25.95
Written in collaboration
with LIA Foundation
Author, Health Care Journalist
Read Bryan's Preface
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The Lyme-Autism Connection
Book was featured in this magazine in 2009. Read
287 Pages, $25.95, Paperback
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287 Pages - $25.95
AN INVESTIGATIVE REPORT
— The Lyme-Autism Connection,
a book written in collaboration with the Lyme-Induced
Autism (LIA) Foundation, provides critical new
research on the emerging science supporting a link between Lyme disease
and childhood developmental disorders.
Awareness of the Lyme-autism
connection is spreading rapidly, among both parents and practitioners. Medical
Hypothesis, a scientific, peer-reviewed journal published by
Elsevier, recently released an influential study entitled "The Association Between Tick-Borne Infections, Lyme
Borreliosis and Autism Spectrum Disorders." Here is an excerpt from
hronic infectious diseases, including tick-borne infections such as Borrelia burgdorferi,
may have direct effects, promote other infections, and create a weakened, sensitized and immunologically vulnerable state during fetal development and infancy, leading to increased vulnerability for developing autism spectrum disorders.
An association between Lyme disease and other tick-borne infections and autistic symptoms has been noted by numerous clinicians and parents."
Article Authors: Robert C. Bransfield, M.D., Jeffrey S. Wulfman,
M.D., William T. Harvey, M.D., Anju I. Usman, M.D.
Read the full
the Book's Introduction: The Twin Epidemics
Over the last decade, two disease epidemics have gone from mild ripples in the water to roaring, ravenous, all-consuming tidal waves, destroying thousands of lives and tearing apart countless families.
These two diseases are Lyme disease and autism. Until recently, these afflictions were believed to be unrelated. Actually, that is an understatement. They were believed to have absolutely nothing in common, occupying distinct and opposite positions in the medical field. Whereas bronchitis and
Strep throat have some relationship in that they are both infections, Lyme disease and autism were thought to have nothing in common at all—one is a tick-borne infection which healthy people contract while camping, and the other is a prenatal brain development disorder. Recently, however, science has found similarities between Lyme disease and autism that cannot be ignored. When one looks beneath the surface of these seemingly diverse disorders, the underlying discoveries are shocking.
“When a pregnant woman is infected with Lyme disease, not only is she subject to its devastation, but her baby is too.”
—John Drulle, M.D.
Urgent care and private practice physician
“Accumulation of experimental evidence also points to potential for peri-, pre- and postnatal infections as causes for several neurodevelopmental disorders such as schizophrenia, autism, cerebral palsy and mental retardation.”
—Excerpt from the book “Neuropsychiatric Disorders and Infection,” edited by Hossein Fatemi, M.D., Ph.D., Associate Professor, University of Minnesota Medical Center
“An association between Lyme disease and other tick-borne infections during fetal development and in infancy with autism, autism spectrum disorders (ASD) and autistic symptoms has been noted by numerous clinicians and parents.”
—Medical Hypothesis journal article written by Robert C. Bransfield, M.D., Jeffrey S. Wulfman, M.D., William T. Harvey, M.D., Anju
“An observant parent’s evidence may be disproved but should never be
“Lyme produces a micro-edema, or swelling in the brain. This affects your ability to process information. It’s like finding out that there’s LSD in the punch, and you’re not sure what’s going to happen next or if you’re going to be in control of your own thoughts.”
—Bernard Raxlen, MD,
International Lyme & Associated Diseases Society
“Great diversity of clinical expression of signs and symptoms of gestational Lyme borreliosis parallels the diversity of prenatal syphilis. It is documented that transplacental transmission of the spirochete from mother to fetus is possible…Autopsy and clinical studies have associated gestational Lyme borreliosis with various medical problems including fetal death, hydrocephalus, cardiovascular anomalies, neonatal respiratory distress, hyperbilirubinemia, intrauterine growth retardation, cortical blindness, sudden infant death syndrome, and maternal toxemia of pregnancy.”
—AB MacDonald, Souhampton Hospital, New York, abstract taken from a
“Relapsing-fever borreliosis caused by Borrelia duttonii [a strain of Lyme bacteria] is a common cause of complications of pregnancy, miscarriage, and neonatal death in sub-Saharan Africa…B. duttonii infection during pregnancy results in intrauterine growth retardation, as well as placental damage and inflammation, impaired fetal circulation, and decreased maternal hemoglobin levels…spirochetes frequently cross the maternal-fetal barrier, resulting in congenital infection.”
— Department of Molecular Biology
Umea University, Sweden.
of Contents - 287 Pages
Information for the Reader, 10
Foreword by Robert Bransfield, M.D.,
The LIA Foundation, 13
Introduction to this book, 14
Getting Personal with Bryan and Tami
Bryan’s Preface: The Lyme-Autism Connection Close To Home, 19
Tami’s Preface: Research and Questions Bring New Hope,
An Uphill Battle, 37
The Many Faces of Autism, 41
But Isn't Lyme Disease a Simple
ILADS List: Basic Information About
Lyme Disease, 48
Infection Stew, 52
On The Front Lines, 56
2 Building the Foundation
Congenital Transfer, 59
Pregnancy and Lyme Disease, By John
Drulle, M.D., 62
Recent Studies, 69
Family Disease Trends, 74
Interpreting the Data and Moving Past the Genetics Paradigm, 78
Refuting the Inventible Guilt, 80
3 Immunity and Infections
Building the Case, 83
Autism and Infections, 88
A Few Key Example Infections, 91
4 Making the Connection
The Antibiotic Clue, 97
Primary Lyme-Autism Study, 102
Open Studies, 111
5 Connecting the Dots: Common Symptomology
Symptoms vs. Syndromes, 116
Blurred Lines Between Disease Labels, 117
Lyme Disease: The Great Imitator, 119
Autism: The Next Great Imitator?, 121
Where the Rubber Meets the Road, 129
the Dots: Geographic Distribution
The Correlation Coefficient, 135
Chronological Correlation, 140
Geographical Correlation, 145
Finding a physician, 154
Finding a Lyme-Literate Medical Doctor (LLMD), 158
Finding an Autism-Literate Medical Doctor, 159
Using Internet Discussion Groups to Locate a Physician, 159
Brief Tips for Formulating a Treatment Plan, 160
Treatment Resources, 161
Closing Argument, 165
Appendix A: Testing for Lyme Disease and Co-infections, 169
Appendix B: Introduction to Lyme Disease, 179
Appendix C: Testing for and Treating Heavy Metal Poisoning, 189
Appendix D: The Think Tank Overview, 199
Appendix E: Personal Stories of Mothers
and Families, 224
(allow preview a few minutes to load)
Written by health care
journalist Bryan Rosner and LIA Foundation co-founder Tami Duncan, this
book set out to investigate the explosive increase in both Lyme
disease and autism cases. The book is based on objective scientific data
as well as the vast wisdom and experience of physicians, researchers and
parents. The book was written to explore the simple question, Is
there a significant connection between the exploding rates of Lyme
disease and autism, and if so, what are the mechanics of that connection? Although the Lyme-autism connection is an area of research
that is brand new and continually developing, there is an ever-increasing amount of information and science to support the connection hypothesis. The following are some of the discoveries which were made by the authors and presented in the book:
spanning the last 30 years have shown that Borrelia burgdorferi (the
causative bacteria in Lyme disease) can be transmitted from mother to baby during pregnancy, resulting in early childhood infection.
John Drulle, M.D., conducted pioneering research in this area in
the 1990's—his work is included in the book.
causes many of the same immune system irregularities that are also
present in Lyme disease.
Numerous infections appear to be involved in autism,
not just Borrelia burgdorferi. Borrelia appears to be one of the more important infections due to its skyrocketing prevalence and epidemic proportions.
The Lyme-autism connection has been substantiated by clinical experience, both in the physician’s office and at home among numerous
observant mothers and fathers.
The symptoms of Lyme disease overlap with the symptoms of autism, and in fact,
the two diseases share in common many of the same “mimicking
diagnoses,” especially mental disorders, such as schizophrenia,
obsessive compulsive disorder, depression, and attention deficit
disorder (ADD). Both Lyme disease and autism are characterized by clustering of these diseases within family histories.
The Lyme-autism connection is being studied with increasing frequency, by researchers with an ever-growing list of qualifications and credentials.
See video previews to your right.
The Lyme-autism connection is comprised of not one or two elements, but instead, numerous puzzle pieces which support one another to create and substantiate the connection hypothesis.
If you intend to take action and apply Lyme disease treatment to your child, please do so only under the supervision of a licensed physician. The
book provides guidelines for finding a helpful
This field is evolving rapidly. To stay up to date, keep connected with the LIA Foundation,
Parents themselves are on
the front lines of this emerging area of research. The following are
experiences of parents in the trenches:
"I would like to thank you so much for introducing me to
The Lyme-Autism Connection. This book has made a tremendous impact on my family and me. My three kids were previously diagnosed with high functioning autism, and I have been experiencing strange progressive multi-system symptoms. After reading your book, I tested myself for Lyme Western Blot IgG and IgM with IGeneX and my tests were positive for Lyme Disease. I then determined that my kids had congenital Lyme Disease which was inducing their high functioning autism. Because of your book, we can now treat the underlying cause of our symptoms and significantly improve our health and future.
I highly recommend The Lyme-Autism Connection for any person with such previous diagnoses as autism, fibromyalgia, chronic fatigue syndrome, multiple sclerosis, and many other chronic conditions. In addition, I believe that every doctor should read this book since we doctors are not taught about the infectious cause of autism and the chronic nature of Lyme Disease in medical school, residency, and continuing education.
This book may change your life. It certainly has change my
autism has become so prevalent that there are very few who do not
know of a family with an autistic child. Families with two autistic
children are not uncommon, and I personally have seen a family in
which all three of the family’s children were autistic (very much
latest statistics estimate that over one half million American
children are autistic, and with numbers steadily growing, there is
no end in sight.
can be expected that treatments will improve the outlook of these
children, but many or most of them will require custodial care for
life, at an average cost to society as much as three million dollars
per child. Something must be stirring this explosive epidemic on,
and one of the factors which has been greatly overlooked is the
Mother of 3 autistic children,
Contributing Writer, and one of the
first researchers to discover the Lyme-Autism connection
Genetics or Infections to Blame for the Autism Epidemic?
Bryan and Tami asked the following questions: Why would cases of autism skyrocket over the past couple of decades? If autism is a genetic disorder, as it has been previously believed, how could such a rapid increase occur? Genetic disorders rarely involve such non-linear, exponential explosions in occurrence. Genes just don’t change that fast. Infectious epidemics, on the other hand, such as Lyme disease, can and do cause exponential increases in disease cases. Also, why do the cases of autism continue to skyrocket even after mercury has been taken out of vaccines, and even in children who were never vaccinated?
Statistics show a strong correlation (as defined mathematically with correlation coefficient) between the rising incidence of autism and the rising incidence of Lyme disease from 1992 to 2006.
There is also a significant correlation (as defined mathematically with correlation coefficient) between the geographic distribution of autism and Lyme disease
cases (See Figure 1 below). This data alone is enough to raise eyebrows.
This figure compares cases of
Lyme disease with cases of autism in the United States during
the 2006-2007 school year. Cases
of Lyme disease are indicated by black bars and cases of autism
are indicated by gray bars. Observe how the states with
the highest incidence of autism are the same states with the
highest incidence of Lyme disease. This unmistakable and
of disease cases in the same states was one of the major
findings of the Lyme-autism study.
Thoughtful House Center for Children / Fighting Autism Foundation
United States Centers for Disease Control (CDC) (Lyme disease
Of course, mere statistical correlation (as seen above in Figure
1) between the incidence and distribution of Lyme disease and autism is not enough to use as a foundation for causation. If you recall your college statistics class, correlation does not necessarily imply causation.
However, when the strong, but not necessarily conclusive, correlations between autism data and Lyme disease data are combined with other factors such as symptomology, epidemiology, family history, and other factors we explore in this book, a very strong argument can be built for the case that similarities between Lyme disease and autism move beyond the realm of correlation into the territory of causation.
For these reasons, the Lyme-autism connection is gaining momentum and public awareness rapidly. Well respected researchers, physicians, and organizations are beginning to take a second look at what might be the biggest infectious
disease discovery of the century.
invite you to explore the shocking data with us.
Awaiting your discovery is the Lyme-Autism Connection.
Written, produced, and sold
in collaboration with
The LIA Foundation
Now Available! Published
July 1, 2008
By Bryan Rosner
With Tami Duncan
Foreword by Robert Bransfield, M.D.
Paperback Book, 287 Pages, $25.95
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