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Table of Contents
Foreword by James Schaller, M.D.
 The Lyme Chronicles
Lyme Disease Basics
Medical Freedom and You
About Bryan Rosner


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Lyme Community Forums
Lyme Disease and Rife Machines
Up-to-the-minute News!
Public Health Alert News Bulletin
Babesia by James Schaller, M.D.
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"Broad and clearly written, this will be one of the top Lyme Disease books of the decade. Bryan Rosner is unusually gifted at explaining new emerging treatments. He thinks big and offers big solutions." 

      - James Schaller, M.D.
        Author of 16 books and
        Published in 25 journals

"I am a sleep lab technologist, and I have chronic Lyme Disease. Before I found a Lyme doctor, I was forced to educate myself about this disease. I have an arsenal of over 25 Lyme Disease books. Bottom line, Bryan Rosner's books surpass any I have in my collection. The Lyme Disease epidemic will be coming to a neighborhood near you and this book could be your defense against this insidious attacker."

      - Tracie Schissel, PSGT
        Brainerd Lakes Sleep 
        Health Center

"Having lived myself with chronic Lyme Disease for over 10 years, I wish I had the information available in this book years ago. Everyone with chronic Lyme Disease will relate to and benefit from this book."

      - Scott Forsgren 
        Founder and Editor of

"Bryan Rosner has written another ground-breaking Lyme Disease book. The Top 10 Lyme Disease Treatments is a perfect compliment to his first book. It expands on information in the first book and also contains new treatments from traditional and alternative medicine. Rosner frankly discusses the many difficult medical and political issues in today's Lyme Disease treatment climate. A must-read book!"

      - Jeff Mittelman
        Moderator of the
        Lyme-and-Rife Group

"I am a registered nurse, wife, mother, and patient, and for 15 years I have suffered from three tick borne diseases. I have searched the world over looking for healing. Hope is a word Lyme sufferers soon learn is not part of their vocabulary.

Bryan Rosner opens the door to hope and offers a map to restored health. By turning the pages of this book, you will learn how to turn the course of suffering. A former Lyme sufferer himself, Rosner has paved the way, thank God, for all of us." 

      - Mary E. Brescia, R.N.

© 2007 BioMed


The Top 10 Lyme Disease Treatments


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Defeat Lyme Disease With The Best Of
Conventional And Alternative Medicine





he Marshall Protocol is perhaps the most significant breakthrough in Lyme Disease treatment since Doug MacLean discovered in the 1980s how to employ a homemade rife machine (see Chapter 5) to heal his own Lyme infection.  The reason the Marshall Protocol is so significant is that it addresses an aspect of the Lyme Disease complex which no other treatment, protocol, supplement or herb can even come close to touching.  The discoveries that led Trevor Marshall, Ph.D., to develop the Marshall Protocol have uncovered and exposed a critical part of the process which Borrelia Burgdorferi uses to establish and maintain infection in the host.  The Marshall Protocol is the only known therapy which addresses this aspect of the bacterial survival process.  If you take the Marshall Protocol out of the Lyme Disease treatment toolbox, there is no comparable tool to replace it.  

The protocol builds on the work of Dr. Lida Mattman, one of the most influential medical scientists in modern history. With a master's degree in virology from the University of Kansas and a Ph.D. in immunology from Yale University , Lida Mattman has revolutionized the study of infectious disease and established the foundation for decades of progress in science and medicine.  A 1998 nominee for the Nobel Prize in Medicine, Mattman found that a certain type of bacteria lacking a cell wall (known as cell-wall-deficient, variant, or L-form bacteria) are not only very common but are also the root cause of multiple health conditions that have baffled medical scientists for years.  The presence of cell-wall-deficient pathogens in the human body is extremely difficult to detect and has thus been largely ignored by conventional medicine.  

Dr. Mattman's studies have forced hundreds of physicians and researchers to accept the fact that this elusive and highly complicated class of bacteria is responsible for many previously-misunderstood ailments.  Interestingly, Mattman's research findings bear a striking resemblance to the conclusions about microorganisms drawn by Dr. Royal Raymond Rife himself.    

Although her breakthrough discoveries caused a light-speed acceleration in the field of bacteriology, no one has been able to figure out exactly what to do about the cell-wall-deficient bacteria identified by Dr. Mattman.  We know they are there, and we know they cause many diseases considered untreatable or incurable by conventional medicine, but getting rid of them is a different story.

Fortunately, there is a handful of brilliant researchers who are currently studying these pathogens and are discovering ways to attack cell-wall-deficient bacteria, destroy them, and thereby heal incurable diseases.  Trevor Marshall, Ph.D., is one such researcher.  After failing to gain benefit from conventional treatment for his own affliction with sarcoidosis (a multi-system disorder characterized in affected organs by inflammatory lesions), Marshall was compelled to take a closer look at the pathogenesis of chronic disease.  His research conclusions were very similar to those reached by Dr. Mattman:  a surprisingly long list of chronic diseases are actually caused by cell-wall-deficient bacteria.  Sarcoidosis and Lyme Disease, for example, share this root cause. If you are confused because you thought Lyme Disease was caused by spirochetes, not cell-wall-deficient bacteria, keep reading, we will answer that question.

Decades of studies by Dr. Marshall led him beyond the ability to merely identify cell-wall-deficient bacteria and their role in various disease processes.   In developing the protocol which bears his name, he has created the means to actually counter their bacterial activity.  The Marshall Protocol is a ground-breaking method of killing cell-wall-deficient bacteria in the human body and ultimately curing the previously untreatable diseases this pathogen causes.  After Marshall employed his discoveries to treat sarcoidosis and heal himself, he went on to establish The Autoimmunity Research Foundation through which he collaborates with physicians and researchers around the world to help chronically ill people recover from various afflictions.   Marshall has bridged the gap between simple awareness of the existence of cell-wall-deficient bacteria and knowledge of how to eradicate them.

Clarification of the root cause of Lyme Disease may be needed here.  As mentioned earlier, the Lyme Disease pathogen, Borrelia Burgdorferi, exists in three distinct forms:  spirochete, cyst, and cell-wall-deficient form.  It is popularly (and erroneously) believed that the spirochete form of the disease is the only form—quite often, researchers and practitioners ignore the other two forms.  This ignorance is the result of antiquated, inaccurate, and close-minded educational materials commonly presented at medical schools. In actuality, according to a burgeoning heap of published research, the spirochete form is in fact just a small part of the whole disease picture.  Let's take a small detour to examine the three bacterial forms of Borrelia Burgdorferi.

Although not the totality of the disease, the spirochete form is highly dangerous and significant.  It is responsible for the initial, rapid spread of the infection throughout the body and various organs due to its highly-mobile, drill-capable shape.  The spirochete form is also responsible for many ongoing symptoms. It is, however, simply not the whole story.

The second form of Lyme Disease bacteria is the cyst form, which is also commonly ignored by mainstream practitioners and researchers.  The cyst form is a symptomless, protective, survival-oriented form that is elusive, difficult to identify in laboratories, and nearly impossible to kill.  Further discussion of the cyst form can be found elsewhere throughout this book and detailed discussion can be found in Lyme Disease and Rife Machines. Additionally, lymeinfo.net has an extensive collection of cyst form-related research and published studies.

The third form of Lyme Disease bacteria is the cell-wall-deficient form, which happens to be extremely dangerous, insidious, and also the target of the Marshall Protocol.  Many of the most severe symptoms and organ dysfunctions associated with Lyme Disease occur as a result of the presence of cell-wall-deficient bacteria.  Additionally, over time, the population of cell-wall-deficient bacteria tends to increase. This form can actually hide inside cells within the body to avoid detection.  More amazingly, it can actually hide in immune system cells themselves. The cell-wall-deficient form must be addressed in order to heal, yet it is commonly overlooked, or worse, its existence is often completely denied, despite peer-verified research by the likes of such heavyweights as Yale graduate Lida Mattman.

Each of the three bacterial forms is capable of converting to the other forms under certain circumstances.  Spirochetes convert to cell-wall-deficient and cyst forms as a survival tactic (cysts are much more treatment-resistant than spirochetes).  Cysts convert to spirochetes occasionally―usually in spring and fall―as a proliferation tactic, to spread the disease to other tissues (spirochetes are more mobile and can more easily spread the infection than cysts). The cell-wall-deficient form is utilized for various reasons, including, of particular note, the ability of this form to survive numerous treatment approaches, including cell wall inhibiting antibiotics.    

Different antibacterial approaches must be used for each of the three bacterial forms because each bacterial form has different weaknesses and vulnerabilities. Rife machines are highly proficient in killing spirochetes.  Spirochetes can also be killed somewhat effectively with protein synthesis inhibiting antibiotics.  Cysts respond to certain antibiotics (discussed in Chapter 1).  Cysts can also be exposed and destroyed, with proper treatment, timing, and planning, by rife machine therapy.  However, until the Marshall Protocol, there was not an effective treatment for cell-wall-deficient bacteria. There are several types of antibiotics (primarily protein synthesis inhibitors such as the tetracyclines and macrolides) which have activity against cell-wall-deficient bacteria, but these are minimally effective when used alone.  The Marshall Protocol is the first therapy that has actually been able to comprehensively eradicate this form of the bacteria.  This is why the Marshall Protocol is so important.  Before the Marshall Protocol, there was simply no way to deal with the cell-wall-deficient form of Lyme Disease.  Hence, before the Marshall Protocol, recovery was much more difficult to attain.

I first heard of the Marshall Protocol through Ron, a friend and fellow Lyme Disease sufferer who often participates in the Lyme-and-Rife online discussion group.  Just as I had, Ron had benefited from rife machine therapy but still needed something to finish off the disease.  Ron was tremendously successful with the Marshall Protocol.  After due consideration I decided to try the protocol myself.  Sure enough, results were forthcoming, and I couldn't help but notice that the Marshall Protocol seemed to provide improvement in areas where rife machine therapy lagged.  The longer I researched, used myself as a guinea pig, and consulted with various patients and practitioners, the more obvious it became that the Marshall Protocol would play an important role in Lyme Disease recovery.  As mentioned, it addresses an aspect of the Lyme Disease complex that, quite simply, no other treatment, supplement, or protocol can impact.

Those who use rife machines to fight Lyme Disease will be excited to find out that the Marshall Protocol appears to be compatible with rife machine therapy.  More than compatible, actually.  Each therapy compensates for weaknesses in the other.  Because the method of action of the two therapies is entirely different, it is not redundant to use both during the course of a Lyme Disease treatment campaign.  The therapies work together to accelerate the healing process.

The answer to many incurable, idiopathic diseases

The benefit provided by the Marshall Protocol does not stop with Lyme Disease.  Thousands of actual patients with real medical conditions ranging from fibromyalgia and chronic fatigue syndrome to arthritis and obsessive-compulsive disorder have regained their health by using the Marshall Protocol.  Their stories are very instructive.  To communicate with thousands of Marshall Protocol users visit the discussion forum located at marshallprotocol.com.

The commonality which allows such differing illnesses to be treated successfully by the Marshall Protocol is their root cause:  cell-wall-deficient bacteria.  Visit marshallprotocol.com for a full list of conditions which may profit from the Marshall Protocol.  Of course not all allegedly untreatable diseases are caused by cell-wall-deficient bacteria.  Some such diseases may be caused by other pathogens or even problems like mercury poisoning and allergies.  However, a large number of serious diseases are caused (or at least contributed to) by cell-wall-deficient bacteria and will respond accordingly to the Marshall Protocol.  

Modern conventional medicine does not test for cell-wall-deficient bacteria during the process of diagnosing diseases.  Hence, there is a wide range of symptom presentations having these bacteria as a root cause which end up being diagnosed with nonsense disease labels such as “fibromyalgia,” "chronic fatigue syndrome," or "depression.”  These disease labels (and many others like them) are flawed because they provide only a description of symptoms but absolutely no useful information about the cause of the problem.  Such diseases are those known in the conventional medical community as "idiopathic."  The word means “without known cause” but is really just a fancy way to say "we have no idea what is wrong with you."  Diagnosing muscle pains with the label “fibromyalgia” is like diagnosing a broken transmission in your car with the label “It Just Don’t Work No More.” Patients are told that there are no successful remedies for their diseases other than symptom-reducing, palliative treatments, because frankly, how could there be a successful remedy if no one knows what is causing the problem?

In many cases, the Marshall Protocol offers the only hope to people with idiopathic diseases, because the Marshall Protocol operates from a position of recognition and understanding of the actual problem, not just the symptoms.

While no one knows exactly how cell-wall-deficient bacteria infiltrate the body, or why some people are more susceptible to them than are others, open-minded scientists have long suspected their involvement in many health conditions deemed idiopathic.  For example, consider autoimmunity, which is often alleged as the cause of diseases like those mentioned in the above paragraphs.  Defined as an attack on the human body by its own immune system, autoimmunity itself has been hypothesized to be triggered by stealth pathogens (like cell-wall-deficient bacteria) which short circuit and confuse the immune system to the point of self-attack.  It has been hypothesized that such stealth bacteria could hide away in host tissues, leading the immune system to mistake healthy, host tissues for the invading bacteria.  The Marshall Protocol has helped to confirm this hypothesis; many people with autoimmune disorders have gained significant improvement, or even complete recovery, via the protocol.  People with so-called "autoimmunity" are actually getting better when they are treated for stealth bacterial infections.

It may be difficult to understand and accept that cell-wall-deficient bacteria can cause diseases with so many diverse symptoms and presentations—from musculoskeletal disorders to mental disorders.  The following three points help to explain why many diseases, commonly believed to be unrelated, can all be caused by cell-wall-deficient bacteria:  

  1. As a result of varying genetics, environmental factors, and other variables, illness will manifest differently in different individuals, leading to unrelated diagnoses despite analogous causes.

  2. Many, possibly thousands, of different species of cell-wall-deficient bacteria exist, each having unique deleterious effects, leading to varied presentation of disease.

  3. Cell-wall-deficient bacteria are capable of infecting every major organ and system in the body; the syndrome or disease label someone ends up with often depends on where a cell-wall-deficient bacterium establishes infection.

An analogy will further clarify how different diseases and different symptoms can have the same root cause: Allergies.  Many people are allergic to pollen, yet allergic reactions vary greatly; some people get runny noses, others get asthma, some get red, itchy eyes.  Some allergic reactions are only an uncomfortable nuisance, while others are life-threatening.  In the same way, people react to infection by cell-wall-deficient bacteria differently—some moderately, some severely, typically all with symptoms that share some aspects in common but still vary wildly, as is the case with most idiopathic diseases.  An interesting side note:  many diseases which are caused by cell-wall-deficient bacteria result in part from allergic reactions to their bacterial toxins.  

The bottom line is simply that many diverse diseases share the root cause of cell-wall-deficient bacteria. Because a multiplicity of conditions can be caused by cell-wall-deficient bacteria, the Marshall Protocol has applicability to many seemingly unrelated illnesses.  If you or someone you know sufferers from an unmitigated disease, it is possible that it is caused by stealth bacteria unrecognized by conventional medicine.  You have everything to gain and nothing to lose by exploring what the Marshall Protocol offers.

Now we will examine what the Marshall Protocol is and how it works. First we will look at the general principles and discoveries on which the protocol is based, and then we will look at the actual treatments and lifestyle recommendations that comprise the protocol.  

Marshall Protocol principles

Vitamin D dysregulation

Also known as calciferol, Vitamin D was misnamed as a vitamin after its discovery in 1922.  A vitamin is a type of organic substance that is required in the diet and essential to nutrition and metabolism.  Vitamin D is unique because it is not required in the diet; instead, it is manufactured by the body via exposure to sunlight or artificial lights. Although we do consume Vitamin D in our diets, it is not technically a vitamin since it is not required in the diet.

For the purpose of explaining the Marshall Protocol, we are less concerned about the technical definition of Vitamin D and more concerned about how it affects chronic disease.  Whether a true vitamin or not, Vitamin D plays a critical role in the pathogenesis of Lyme Disease and other illnesses involving infection with cell-wall-deficient bacteria. At the center of the Marshall Protocol is the breakthrough discovery that Vitamin D is not handled correctly in the bodies of people infected with cell-wall-deficient bacteria. Let’s look at how this dysregulated handling of Vitamin D occurs.

As we mentioned, Vitamin D can enter the body in two ways: it is either synthesized in the skin after exposure to sunlight or artificial lights, or it is consumed in the diet. Once Vitamin D is inside the body, not all of it remains in static form. A small portion of Vitamin D is converted to a type of secosteroid known as 1,25 dihydroxyvitamin-D (abbreviated “1,25-D”).  A hormone required for regular body function, 1,25-D is manufactured by the kidneys as a metabolite (or product) of Vitamin D. In healthy people, the body tightly regulates how much 1,25-D is made in the kidneys; although critical to health, too much 1,25-D can be very harmful. If present in excessive quantities, 1,25-D can be immunosuppressive and cause a plethora of physical and psychological symptoms.

In people infected with cell-wall-deficient bacteria, the production of 1,25-D can spiral out of control and rapidly reach damaging levels.  This happens because, as an evolved survival mechanism, cell-wall-deficient bacteria are capable of catalyzing the process by which Vitamin D is converted to 1,25-D.  Instead of a slow, controlled conversion which occurs only in the kidneys, 1,25-D production becomes uncontrolled, occurring throughout the body inside cells infected with cell-wall-deficient bacteria. Specifically, immune system cells harboring cell-wall-deficient bacteria can turn into tiny, unrestrained factories producing excessive amounts of 1,25-D. Bacteria catalyze the 1,25-D conversion process intentionally to cause immune system suppression and create a more favorable living environment in the body.  

The result of catalyzed 1,25-D production is a subclinical yet devastating immunosuppression syndrome that allows Lyme Disease (and other types of cell-wall-deficient) bacteria to persist chronically in the body.  When present in appropriately controlled quantities, 1,25-D is a critical nutrient and is important to health, as we have said.  However, when present in excessive quantities, 1,25-D is immunosuppressive and inhibits the immune system from fighting infections. This process is one of the core survival mechanisms of Borrelia Burgdorferi.  The excessive levels of 1,25-D often present in people harboring chronic infections leads to a greatly inhibited host defense system. By accelerating conversion of Vitamin D to 1,25-D, these tiny bacteria are basically able to neutralize the human immune system.  

Additionally, as we have alluded to, elevated levels of 1,25-D itself (even without infections on board) can cause a plethora of disease symptoms.  So, an elevated level of 1,25-D has a two-fold impact: it suppresses the immune system and also creates numerous other symptoms of malaise. This is why it is so important to address elevated 1,25-D levels when treating Lyme Disease.

The aforementioned principles are at the core of the Marshall Protocol.  One of the primary objectives of the Marshall Protocol is to reduce the excessive levels of 1,25-D in the body.  Since 1,25-D is a metabolite of (or product of) Vitamin D, the process of reducing 1,25-D levels in the body requires that a person suffering from infection with cell-wall-deficient bacteria decrease their consumption of Vitamin D foods and supplements, and also reduce their exposure to sunlight and bright lights. Both of these actions are primary components of the Marshall Protocol that will be examined in a few pages. By curtailing the amount of Vitamin D that enters the body, 1,25-D production is also reduced, bringing the immune system back into balance. While Vitamin D consumption (and exposure to sunlight and other artificial lights) may be neutral or even beneficial to healthy people, it can be poison to people infected with cell-wall-deficient bacteria because of this pathogenic process.

In addition to Dr. Marshall, Dr. James Schaller has also found that 1,25-D is involved in other inflammatory processes. Specifically, 1,25-D levels have been found to be higher in inflamed, damaged, and arthritic joints in comparison with healthy joints. This observation further confirms the principles on which the Marshall Protocol is based.  

Now that you have some background in the nuances of Vitamin D, we’ll turn our attention back to the role Vitamin D plays in the Marshall Protocol.  In the Marshall Protocol, the goal is to reduce excessive 1,25-D levels (which are almost always present in Lyme Disease sufferers). This is accomplished by intentionally avoiding exposure to sunlight and bright lights and by decreasing consumption of Vitamin D-containing foods and supplements. We will further discuss these topics in a later section of this chapter.  First, though, before moving on, I am sure some of my readers will be scratching their heads and wondering if they should actually consider Vitamin D reduction as a valid Lyme Disease therapy.  Let's take a small detour with some additional discussion of that issue.

It is natural to be skeptical that intentional reduction of Vitamin D in the body could be healthy.  Vitamin D supplements line the walls of your favorite health food store.  Vitamin D may be a part of your daily supplement routine.  New research is available almost daily detailing the benefits of Vitamin D. However, you need to shift the platform from which you view Vitamin D.  Any good thing can become a bad thing under certain circumstances.  Water, for example, is essential to sustaining life, but it can also cause death.  No one would tell a drowning person not to worry because water is our friend.  Vitamin D is no different.  People infected with cell-wall-deficient bacteria will find that Vitamin D can and does become toxic.  The effects of elevated levels of the Vitamin D metabolite known as 1,25-D are, quite frankly, responsible in part for the word “chronic” in “chronic Lyme Disease.”

There is no one-size-fits-all formula for Vitamin D. Some health conditions may benefit from its supplementation, while others are harmed. Consider, for example, the analogous nutrient, iron. Too much iron makes you very sick (my father has this condition, called hemochromatosis, and has to give blood every couple weeks to lower his iron levels). Conversely, we all know that too little iron leads to anemia. In the case of iron it would be misguided to argue about whether iron is good or bad. The right amount is good, and the wrong amount is bad. The same is true of Vitamin D―in some cases it may be too low, and, in other cases, too high.

If you need objective verification that your 1,25-D levels are in fact abnormal, several laboratory tests are available. These tests look at levels of 1,25 dihydroxyvitamin-D, 25 hydroxyvitamin-D and angiotensin-converting enzyme. The codes for these tests are LabCorp #081091, #081950, and #010116, respectively. A physician trained in applying the Marshall Protocol can help you understand, order, and interpret these tests. You can get a referral to such a physician and learn more about these tests at marshallprotocol.com.

If you do not have access to a Marshall Protocol-trained physician, the tests are still worth doing because they can help you convince your current physician that your Vitamin D levels are indeed problematic and that the medications and lifestyle modifications advocated by the Marshall Protocol are indicated.  Test results are also helpful for patients themselves to see, as they can objectively identify Vitamin D dysregulation and establish that the protocol may be helpful. Seeing objective test results can dispel doubt in the protocol and establish a scientific basis for its use.  

In the case of Lyme Disease, laboratory tests, while helpful, are not a necessary prerequisite to proceeding with the protocol. The tests can be quite expensive and are often not covered by health insurance. I personally never had Vitamin D tests done.  The results of these tests are not always a perfect indicator of the treatment’s potential usefulness and should not in any case be relied on too heavily. In lieu of or in addition to the tests, a therapeutic trial of the protocol can potentially determine whether or not a specific patient will find benefit.  

Because the goal of reducing Vitamin D in the body is so unusual, many of you may be wondering why you should even consider it at all.  After learning the basic principles of this protocol, I was asking the same question.  However, after using the protocol, the answer became clear: I used the protocol because it works.  It provided enormous, sustained improvement even after many other therapies failed.  This improvement did not occur overnight, and there were some counterintuitive experiences along the way.  We have already seen some of the counterintuitive principles involved in the Marshall Protocol, but lets take a closer look to ensure that these important concepts are fully covered.

As we have said in the Spotlight on Vitamin D SideBox, people infected with cell-wall-deficient bacteria may actually feel better with higher levels of Vitamin D on board, but this leads ultimately to increased severity of their disease.  As Vitamin D is converted into 1,25-D by cell-wall-deficient bacteria, immune system activities (inflammation) are diminished.  This results in a symptom-reducing effect.  The superficial improvement experienced may even lead Lyme patients to seek out Vitamin D sources.  The appropriate course of action, in actuality, is to reduce levels of Vitamin D in the body.  

When Vitamin D levels are lowered to the point that bacteria are no longer able to stimulate production of 1,25-D, the immune system can again begin to perform properly.  Herx reactions will accompany the reviving immune system as it begins to attack the infection and kill bacteria.  If you have read Lyme Disease and Rife Machines, recall that herx reactions are a necessary, albeit uncomfortable, part of the recovery process. Be aware that it is easy to misinterpret what is actually going on.  Herx reactions that occur as Vitamin D levels are lowered may seem like worsening of the disease. These herx-related symptoms may even be misinterpreted as Vitamin D deficiency. In reality, such symptoms are not indications of disease worsening, nor are they signs of Vitamin D deficiency, but instead, they are indications of true healing.

In the short term it is easy to conclude that the Marshall Protocol’s Vitamin D reduction is harmful—it seems to increase symptoms.  It is also natural to conclude that Vitamin D supplementation is beneficial—symptoms are alleviated.  Because of this confusion and the counterintuitive nature of Vitamin D’s effects in someone infected with cell-wall-deficient Lyme bacteria, it is important to study thoroughly and understand fully the Marshall Protocol.  Vitamin D avoidance can be confidently relied on only if you feel comfortable in your understanding of its mechanism of action.

Please remember that the information in this chapter about Vitamin D is experimental and investigational.  There may be negative side effects to Vitamin D reduction.  Consult your physician.

Amplified Effects of Antibiotics

The second foundational principle on which the Marshall Protocol is based is intimately connected with restoration of proper Vitamin D regulation: upon restoring healthy 1,25-D levels, not only is the immune system revived, but another related, and very significant, benefit is seen.  Also at the core of the Marshall Protocol is the breakthrough discovery that standard pharmaceutical antibiotics have greatly enhanced effect when Vitamin D levels are properly balanced.  This was first discovered by Dr. Marshall in relation to treating his own case of sarcoidosis.

In the past, sarcoidosis patients have received only minimal benefit from antibiotic therapy. But Dr. Marshall discovered that, upon reduction of 1,25-D levels, sarcoidosis patients can actually be cured with antibiotic therapy.  Eventually, dozens of people with other chronic illnesses (including Lyme Disease) discovered the same to be true:  having given up on antibiotic therapy due to disappointing results, they found relief and even remission when taking antibiotics after reducing 1,25-D levels.  These discoveries launched the Marshall Protocol:  a program that eradicates cell-wall-deficient bacteria by utilizing a coordinated schedule of particular antibiotics in combination with various methods of Vitamin D control.

When Vitamin D levels are appropriately reduced (which leads to decreased production of 1,25-D), antibiotics not only work better, they can become hyper-effective.  So effective, in fact, that only a minuscule dose is needed to elicit powerful antibacterial action.  This outcome is seen even in patients who have previously failed to respond to high-dose antibiotic therapy.  For example, someone who previously experienced only mild benefits when taking 300mg/day of minocycline will experience dramatic benefits during use of the Marshall Protocol even though doses as low as 10mg/day may be used. Incredible, isn't it?

The amplified effect of antibiotics has a twofold benefit.  First, it means that antibiotics will actually start to work for people who had not previously responded to them; and second, it means that antibiotic side effects are kept to a minimum during use of the protocol because doses can be kept low.  This is great news!  The Marshall Protocol solves two of the primary problems facing Lyme Disease sufferers:  the marginal effectiveness of antibiotics and the toxic side effects associated with their use. Of course, increased effectiveness of antibiotics also means that herx reactions can be much more severe, thus, special care and caution is necessary.  


The above excerpt is only a sample from the Marshall Protocol chapter of the book "The Top 10 Lyme Disease Treatments."

Buy the complete paperback book or buy this chapter as a PDF e-book to read the rest of the chapter. The following are additional sections included in this chapter...

  • Marshall Protocol Components

  • Correcting Vitamin D Levels

  • Reducing Exposure to Sunlight and Bright Lights

  • Avoiding Vitamin D Sources in Food and Supplements

  • Benicar Lowers Vitamin D Levels and Weakens the Bacteria

  • Antibiotics used in the Marshall Protocol

  • My experience with and commentary on the Modified Marshall Protocol

  • Trial and error vs. laboratory testing 

  • Rife machines vs. the Marshall Protocol

  • A Final Word

Would you like to learn more before buying the book? Feel free to browse these excerpts, which are available online, free of charge:

PrefaceForewordTable of Contents 

IndexMedical FreedomMarshall Protocol

Lyme BasicsNatural AntibioticsSauna

Bacterial Forms: Spirochete, Cyst, Cell Wall Deficient

The Top 10 Lyme Disease Treatments: Defeat Lyme Disease With The Best Of Conventional And Alternative Medicine 


367 Pages







“In this helpful book, Bryan Rosner presents 10 new Lyme Disease treatments and enough discussion of the science behind them to put the information in context and make it useful. Whether you are under a doctor's care or going it alone, this book will help you make good decisions so you can get better." 

      - Andrew Hall Cutler, Ph.D., P.E.
        Author of Amalgam Illness: Diagnosis and Treatment
        and Hair Test Interpretation: Finding Hidden Toxicities



"Thorough and brilliant. The Top 10 Lyme Disease Treatments covers many little-known yet vital topics, including the holistic use of antibiotics, different forms of Lyme bacteria (which require different treatments), enzymes, the Marshall and salt/Vitamin C protocols, and Rife therapy. An important book for laypeople and health practitioners alike."

     - Nenah Sylver, Ph.D. 
       Author of The Handbook of Rife Frequency Healing
The Holistic Handbook of Sauna Therapy




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