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"A stunning and insightful treatise on the relationship of periodontal and heart disease. Long forgotten in the annals of medicine, oral spirochetosis may be the missing link in explaining the pathogenesis of atherosclerosis. Dr. Nordquist presents a cogent thesis on how treatment of periodontitis may have profound effects on cardiovascular health."
—Robert Miller, DDS, FACD

“Dr. William Nordquist is brilliant. If oral spirochetes are linked with atherosclerotic heart disease, neurological diseases, and inflammation in the mouth and body, the societal impact would be profound. This research may impact every level of health and well-being.”
—Jeanette Magdalene, PhD

“William Nordquist is one of the few geniuses in the dental profession today. He has been relentless all these years to find the true reason why periodontal disease is a direct cause of heart disease. After digesting hundreds of medical articles, treaties and book volumes, Dr. Nordquist formulated a theory that finally exposes the truth: many debilitating chronic diseases can have a single cause and become stealth killers. This book is a masterpiece that should not be overlooked by our professional colleagues.” —Leonard Linkow, DDS DMSc 










Call (530) 541-7200 or Place Your Order Online

161 Pages, $25.95   

The Stealth Killer: 
Is Oral Spirochetosis the Missing Link in the Dental and Heart Disease Labyrinth?

By William D. Nordquist, BS, DMD, MS
161 Pages, $25.95

SUMMARY: In today's cosmopolitan urban population, more than 51 percent of those with root canal–treated teeth probably have infection at the apex of their root. This figure represents millions of possible locations of dental infection. According to Dr. Nordquist's research, any source of bacteria with resulting chronic infection (including periodontal disease) in the mouth may potentially lead to heart disease and other systemic diseases. 

In this groundbreaking book, Dr. Nordquist takes you on the journey of decades of study that has led to one of the biggest medical breakthroughs of the past 50 years. In addition to discovering scientific facts and evidence, you will also find practical tips on how to get help from your dentist and how to properly take care of your mouth. 



Press Release


The discovered relationship between dental and heart disease announced by the United States Surgeon General in 2000 has necessitated a unique cooperation between dentistry and medicine.  Patients who have systemic diseases, such as heart disease, diabetes, and Alzheimer’s disease, also typically have multiple missing teeth.  As a result of the missing teeth, these are the patients who require the services of implant dentists.  Therefore, implant dentistry requires dentists to understand these diseases and the many medicines that these patients are taking to treat their ailments.  

Scientific studies have definitely shown a relationship between periodontal (gum) disease and heart disease.  With this new understanding, the dentist’s roll in medicine has been dramatically elevated.  They are now responsible for diagnosing and treating gum disease because it is related to diseases that affect other parts of the body, not just the mouth.  Is there a cause and effect; dental disease causing heart disease? Are bacteria that cause periodontal disease also causing heart disease?  That seems to be the case.  The recently released book by William D. Nordquist, (The Stealth Killer: Is Oral Spirochetosis the Missing Link in the Dental-Heart Disease Labyrinth?), connects the dots from one hundred plus years of dental and medical research to establish a compelling hypothesis to explain the missing link between dental and systemic disease. These are serious questions and they greatly increase the responsibility of dentists for their patients who need dental implants.  

An extensive review in the medical and dental literature, plus eight years of microscopic investigation in Nordquist’s laboratory, reveals some very important clues in the search for the relationship between dental and heart disease.  Some important facts are:

  1. Both periodontal disease and heart disease are in epidemic proportions in the modern age, especially after World War II.

  2. More people die of heart disease than all other diseases combined.

  3. By the time most people reach a “ripe old age,” they have some form of heart disease.

  4. 75-80% of people have some form of gum disease.

  5. Even though dental disease has been prevalent since the recording of history, it took a very virulent turn in World War I with the disease named after is discoverer Vincent’s infection (Trench Mouth).

    ABOVE: Dr. Nordquist observes spirochetes in a culture from one of his patients. The spirochetes are stunned when an electromagnetic field is applied to the sample. 
  6. Vincent’s disease is primarily a spirochete bacterial infection.  Spirochetes are involved with gum disease today. 

  7. Spirochetes cause other serious diseases, such as, Lyme disease, Syphilis, and stomach ulcers, as well as, other not as well know debilitating diseases.

  8. Microscopic research on Syphilis in the early 1900’ revealed that Syphilis has a unique “life cycle”.  When the bacteria are treated with an antibiotic or the immune system itself attacks it, the bacteria undergo a morphogenic change and become a “spore”.  The disease is almost impossible to completely eradicate.  It has also been reported in the older literature that oral spirochetes also produce these “spores”.  Research has shown that the Lyme disease Borrelia spirochete also has a similar life cycle and produces “spores” and “cyst” forms.

  9. This “life cycle” of oral bacteria makes the treatment of gum disease very difficult, if not impossible.  Once periodontal surgery is done, if not done on highly compliant patients, it usually returns and addition surgeries are required, but the surgeries rarely ever cure the disease.

  10. Bacteria cause gum disease.  Eliminating these bacteria before it causes disease is the key to curing gum disease, not surgery necessarily.  Surgery maybe needed to help in the decontamination process.  Bacteria eradication treatment is paramount.

  11. Could oral spirochetes and their unique “life cycles” have something to do with heart disease?  Almost certainly.

Research is now being initiated on a grand scale into this relational problem between dental and heart disease.  Many more theories and solutions will be reported as dentists and doctors work together to better understand and treat this problem. 


Book's Table of Contents


About the Author

Author's Autobiography


How Bacteria Influenced My Early Dental Practice

Chapter 1: A Paradigm Shift

Chapter 2: Basic Principles of Atherosclerotic Heart Disease

Chapter 3: Periodontal Disease and Its Many Bacteria

Chapter 4: Clues Learned from Other Spirochetal Diseases

Chapter 5: Oral Spirochetosis Associated with Dental Implants

Chapter 6: Inflamed and Infected Teeth

Chapter 7: Multiple Missing Tooth Syndrome

Chapter 8: The History of Periodontal Disease

Chapter 9: The Course of Oral Spirochetal Illness

Chapter 10: Is Today’s Treatment of Periodontal Disease Enough?

Chapter 11: Treating Periodontal Disease in Its Early Stages

Appendix I

Appendix II

Endnote Citations

Sample Figures

FIGURE 33: One of the cystic bacterial forms Dr. Nordquist observed in the mouth of a patient. Radiating from the cyst are dozens of granules and large spirochetes.

FIGURE 48: Bone loss around newly placed dental implants in one of Dr. Nordquist's patients. The bone loss is most likely a result of spirochete infection. 


About the Author

Dr. William Nordquist is committed to excellence and has practiced dentistry in San Diego, California, since 1973. He received his Bachelor of Science in chemistry from the Rochester Institute of Technology (RIT) and worked for Eastman Kodak Company as an organic chemist. 

He received his Doctorate of Dental Medicine (DMD) and Master of Science from the University of Louisville. His Master of Science thesis and research produced many publications relating to surface chemistry of dental enamel and powdered and blocks of fluoro and hydroxyapatite (HA). He completed a general practice residency at the San Diego Naval Regional Medical Center and achieved the rank of lieutenant commander before leaving the Navy and setting up his private practice of dentistry in San Diego in 1976. He is a fellow in the American Academy of Implant Dentistry (AAID) and a diplomat in the American Board of Oral Implantology/Implant Dentistry (ABOI). Dr. Nordquist was named the 2008 International Dentist of the Year by the American Academy of Implant Dentistry. 

Dr. Nordquist is performing ongoing research and a blog has been created to allow you to follow his work. On this page you will find videos and updates from Dr. Nordquist. The content is easy to access and provides an excellent supplement to this book. To follow Dr. Nordquist’s work, visit his blog.

Dr. Nordquist’s Dental Practice: 
Implant Dentistry of San Diego
2304 6th Avenue
San Diego, California 92101
(619) 236-7959

Place your order for Dr. Nordquist's book today!
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